wetSpring Validation Summary
Life-science and analytical-chemistry spring — 1,962+ tests, 345 scenarios, UniBin single binary, pure primal composition
Status
- 1,962+ tests passing, 0 failed (unit + integration + property + doc)
- 1 UniBin (
wetspring) — 345 scenarios (318 validation + 23 benchmark + 4 composition) - 45 dispatch methods across 22 domains, 50 niche capabilities, 59 consumed
- 56 experiment directories with 64+ frozen JSON baselines
- guideStone Level 5 (primal proof) — V190, live composition health probing, 38/38 NUCLEUS checks
- Zero sovereign HTTP fallbacks — pure primal composition
- Structured gap reports when deployment primals are unavailable
- BLAKE3 content hashing on all data paths
- Build time: 1m44s (down from 25 min with 349 prokaryotic binaries)
- Wave 60 deployment: southGate NUCLEUS 13/13 processes, 11/13 health-responding (2 BTSP-gated), biomeOS 1725 capabilities, Forgejo remotes configured
Key Milestones
- Barrick 2009 SEALED — 7/7 clones, ferment transcript braids delivered to lithoSpore (USB May 19)
- Tenaillon 2016 batch 0 COMPLETE — 5/5 clones, 974 total variants, BLAKE3
623a2b3565a85b52 - UniBin V182 — 349 binaries consolidated into
wetspring single binary, 345 scenarios via clap dispatch - WS-11 v3 calibration — MAPQ gap-based formula, min_mapq=0 (FM-index produces MAPQ=0 for 97%+ reads)
UniBin Subcommands
| Command | Purpose |
|---|
wetspring certify | Layered certification (L0–L6) |
wetspring validate | Two-tier scenario validation (--scenario, --track, --tier) |
wetspring benchmark | Performance benchmarks |
wetspring serve | JSON-RPC IPC server (--socket, --port, --family-id) |
wetspring status | Composition health summary |
wetspring version | Version info |
Notebooks (16)
| # | Notebook | Focus |
|---|
| 01 | Science Validation | 19 IPC methods, validation chain, test distribution |
| 02 | Benchmark Comparison | 23-domain timing, Rust vs Galaxy/QIIME2, energy |
| 03 | Gonzales Deep Dive | IC50, PK decay, tissue lattice, ChEMBL cross-validation |
| 04 | Cross-Spring Connections | Primal consumption matrix, ecosystem flows, sporePrint readiness |
| 05 | Primal Composition Patterns | Pure composition, gap reports, provenance lifecycle, Tier 3 vision |
Science Domains
| Domain | Methods | Key Paper |
|---|
| Microbial ecology | 4 | Community diversity, quorum sensing |
| Bioinformatics | 5 | Alignment, taxonomy, phylogenetics |
| Gonzales immunology | 3 | Gonzales 2014 (DOI: 10.1111/jvp.12065) |
| Anderson physics | 5 | Localization, disorder, hormesis |
| Kinetics | 1 | Gompertz, first-order decay |
| Integrated pipeline | 1 | Full diversity + QS + Anderson |
Active Gaps
| # | Gap | Owner | Priority | Status |
|---|
| WS-9 | Cross-tier parity (L3) | wetSpring | MEDIUM | L1/L2 done, L3 pending live trio |
| WS-11 | Variant caller calibration | wetSpring | HIGH | v3 deployed, Tenaillon batch 0 complete |
See Also